Proteins, proteomics


A binding domain is that sequence of amino acids in a protein/protein family to which a specific ligand binds. As such, domains are vital to a protein's or enzyme's function. A structural domain is a self-stabilizing structural element that may fold independently of the rest of the protein chain.

Specific examples of domains:
cadherin repeats
carbohydrate-recognition domain (CRD)
caspase recruiting domains, CARD domains
C-lectin domain (CRD)
C-type-lectin-like domain (CTLD)
death domain (DD), death effector domain (DED) binds adaptor protein FADD (Fas-Associated Death Domain)
EF-hand domains
kringle domains
pleckstrin homology (PH) domain family
SH2 domain - Src homology 2 domain = p-Tyr recognition domains
zinc finger DNA binding domains

Others (on Wiki) Arginine Finger, Armadillo repeats, Basic Leucine zipper domain (bZIP domain), Phosphotyrosine-binding domain (PTB)

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