Haptoglobins (Hp) are acute phase proteins synthesized in response to pro-inflammatory cytokines early in the inflammatory response.
Haptoglobins are alpha-2-globulins that remove free hemoglobin from plasma by forming a stable complex that aids in recycling of heme iron.
Haptoglobins are elevated in inflammation, malignancies (particularly with metastases to bone), trauma, surgery, steroid or androgen therapy, and diabetes.
tags [Proteins] [acute phase] [haptoglobins] [alpha-2-globulins] [inflammation] [cytokine]
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