collagen
Collagen is the chief structural protein of connective tissue in mammals, located mostly in the extracellular matrix. Collagen comprises long chains containing unusually large amounts of proline, together with glycine residues at approximately every third position. Collagen also contains two uncommon derivative amino acids, hydroxylysine and hydroxyproline (Hyp), where hydroxylysines in some collagens have attached disaccharides.
The tropocollagen subunit is a rod (300 nm x 1.5 nm) comprising three polypeptide strands, each of which is a left-handed helix (not an α helix). Collagen self-assembles, and the precise alignment of individual collagen molecules produces a characteristic pattern of light and dark bands across the fibril on electron-microscopy [] ce-tem collagen fibril [].
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tags [Proteins] [collagen] [connective+tissue] [ECM] [extracellular+matrix]
The tropocollagen subunit is a rod (300 nm x 1.5 nm) comprising three polypeptide strands, each of which is a left-handed helix (not an α helix). Collagen self-assembles, and the precise alignment of individual collagen molecules produces a characteristic pattern of light and dark bands across the fibril on electron-microscopy [] ce-tem collagen fibril [].
Alphabetic links to Glossary items:◦ A ◦ B ◦ C ◦ D ◦ E ◦ F ◦ G ◦ H ◦ I ◦ J ◦ K ◦ L ◦ M ◦ N ◦ O ◦ P ◦ Q ◦ R ◦ S ◦ T ◦ U ◦ V ◦ W ◦ X ◦ Y ◦ Z ◦ o-o animation index o-o diagram index o-o image index o-o micrograph index o-o table index o-o sem/tem index o-o video index .
Companion Sites : Gray Sites α Abiogenesis & Evolution √ Algorithms of Evolution ¤ Cancer סּ Cell Biology ~ Chemistry of Life Ω Complex Systems ººº Cyanobacteria ◊ Enzymes ₪ Evo Devo Ơ Fat ф Immunology »» Mechanisms of Evolution ○ Molecular Biology ** Origin of Life ◘ Paleogeology § Protein ¿ Refuting ID ǒ Serial Endosymbiosis ζζ Sleep ∩ Stromatolites † Taxonomy Phylogeny ọ Tissue ۰۰ Virus • White Sites Diagrams & Tables æ Eubacteria & Archaea φ Molecule → Molecular Paths ››› Pathways ☼ Photosynthesis • Black Sites Ǒ Endosymbiosis ō Organics •
tags [Proteins] [collagen] [connective+tissue] [ECM] [extracellular+matrix]
Labels: collagen, extracellular, matrix, structural
. . . since 11/21/06
