coagulation factors

Coagulation factors participate in the coagulation cascade, which is initiated within 20 seconds of an injury to the endothelial cells that line blood vessels (primary hemostasis, acute phase reaction).

Coagulation factors are synthesized by the liver and their production increases in response to pro-inflammatory cytokines released in the acute phase early in the inflammatory response, in particular:
● factor VIII
● fibrinogen
● plasminogen
● prothrombin
● von Willebrand factor

tags [Proteins] [acute phase] [coagulation factors] [clotting cascade] [cytokine] [hemostasis]